SELF-ASSEMBLING NANOVACCINE CONFERS COMPLETE PROTECTION AGAINST ZIKA VIRUS WITHOUT CAUSING ANTIBODY-DEPENDENT ENHANCEMENT

Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement

The Zika virus (ZIKV) epidemic poses a substantial threat to the public, and the 30hh bikini development of safe and effective vaccines is a demanding challenge.In this study, we constructed a kind of self-assembling nanovaccine which confers complete protection against ZIKV infection.The ZIKV envelop protein domain III (zEDIII) was presented on re

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A case of hypocomplementemic urticarial vasculitis syndrome complicated by eosinophilic pneumonia: a case report and review of the literature

The primary symptom of urticarial vasculitis (UV), which is a histopathological leukocytoclastic vasculitis disease, is an eruption that resembles urticaria.Other organs may also experience accompanying symptoms.Lung lesions with UV are mostly obstructive pulmonary disease with smoking.However, the coexistence of eosinophilic pneumonia (EP) and com

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Prediction of Deoxypodophyllotoxin Disposition in Mouse, Rat, Monkey and Dog by Physiologically-based Pharmacokinetic Model and the Extrapolation to Human

Deoxypodophyllotoxin (DPT) is a potential anti-tumor candidate prior to its clinical phase.The aim of the study was to develop a physiologically-based pharmacokinetic (PBPK) model consisting of 13 tissue compartments to predict DPT disposition in mouse, rat, monkey stickers logos dallas cowboys and dog based on in vitro and in silico inputs.Since l

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Larval development of Spodoptera eridania (Cramer) fed on leaves of Bt maize expressing Cry1F and Cry1F + Cry1A.105 + Cry2Ab2 proteins and its non-Bt isoline

This study aimed to evaluate, in controlled laboratory conditions (temperature of 25±2 °C, relative humidity of 60±10%, and 14/10 h L/D photoperiod), the larval development of Spodoptera eridania (Cramer, 1784) (Lepidoptera, Noctuidae) fed with leaves of Bt maize expressing Cry1F and Cry1F + Cry1A.105 + Cry2Ab2 insecticide proteins and its non-B

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